null

SMILES: CN(C)[C@]1(CC[C@]2(CN(C(=O)N2CC2CCC2)c2ccnc(n2)C#N)CC1)c1ccccc1

InChI Key: InChIKey=GZZWFHJHLURUGF-WMPKNSHKSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 469405   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM469405 (US10807988, Example SC_3048 | cis-4-[1-(Cyclobuty1...) Show SMILES CN(C)[C@]1(CC[C@]2(CN(C(=O)N2CC2CCC2)c2ccnc(n2)C#N)CC1)c1ccccc1 |r,wU:6.11,3.2,(5.33,-24.84,;3.85,-24.44,;3.45,-22.95,;2.76,-25.53,;1.99,-26.86,;.45,-26.86,;-.32,-25.53,;-1.23,-24.28,;-2.69,-24.76,;-2.69,-26.3,;-3.94,-27.2,;-1.23,-26.78,;-.75,-28.24,;-1.78,-29.38,;-3.32,-29.38,;-3.32,-30.92,;-1.78,-30.92,;-3.78,-23.67,;-5.27,-24.07,;-6.36,-22.98,;-5.96,-21.49,;-4.47,-21.09,;-3.38,-22.18,;-4.07,-19.61,;-3.67,-18.12,;.45,-24.2,;1.99,-24.2,;3.69,-26.75,;3.1,-28.17,;4.04,-29.4,;5.57,-29.2,;6.16,-27.77,;5.22,-26.55,)| Show InChI InChI=1S/C26H32N6O/c1-30(2)26(21-9-4-3-5-10-21)14-12-25(13-15-26)19-31(23-11-16-28-22(17-27)29-23)24(33)32(25)18-20-7-6-8-20/h3-5,9-11,16,20H,6-8,12-15,18-19H2,1-2H3/t25-,26+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Grünenthal GmbH US Patent					Assay Description The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...				US Patent US10807988 (2020) BindingDB Entry DOI: 10.7270/Q25Q5060
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM469405 (US10807988, Example SC_3048 | cis-4-[1-(Cyclobuty1...) Show SMILES CN(C)[C@]1(CC[C@]2(CN(C(=O)N2CC2CCC2)c2ccnc(n2)C#N)CC1)c1ccccc1 |r,wU:6.11,3.2,(5.33,-24.84,;3.85,-24.44,;3.45,-22.95,;2.76,-25.53,;1.99,-26.86,;.45,-26.86,;-.32,-25.53,;-1.23,-24.28,;-2.69,-24.76,;-2.69,-26.3,;-3.94,-27.2,;-1.23,-26.78,;-.75,-28.24,;-1.78,-29.38,;-3.32,-29.38,;-3.32,-30.92,;-1.78,-30.92,;-3.78,-23.67,;-5.27,-24.07,;-6.36,-22.98,;-5.96,-21.49,;-4.47,-21.09,;-3.38,-22.18,;-4.07,-19.61,;-3.67,-18.12,;.45,-24.2,;1.99,-24.2,;3.69,-26.75,;3.1,-28.17,;4.04,-29.4,;5.57,-29.2,;6.16,-27.77,;5.22,-26.55,)| Show InChI InChI=1S/C26H32N6O/c1-30(2)26(21-9-4-3-5-10-21)14-12-25(13-15-26)19-31(23-11-16-28-22(17-27)29-23)24(33)32(25)18-20-7-6-8-20/h3-5,9-11,16,20H,6-8,12-15,18-19H2,1-2H3/t25-,26+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	38.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Grünenthal GmbH US Patent					Assay Description The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...				US Patent US10807988 (2020) BindingDB Entry DOI: 10.7270/Q25Q5060
					More data for this Ligand-Target Pair