BDBM46993 5-methyl-3-phenyl-4-(2-tosylpyrazol-3-yl)isoxazole::5-methyl-4-[2-(4-methylphenyl)sulfonyl-3-pyrazolyl]-3-phenylisoxazole::5-methyl-4-[2-(4-methylphenyl)sulfonylpyrazol-3-yl]-3-phenyl-1,2-oxazole::5-methyl-4-{1-[(4-methylphenyl)sulfonyl]-1H-pyrazol-5-yl}-3-phenylisoxazole::MLS001111124::SMR000457058::cid_2745600

SMILES: Cc1onc(c1-c1ccnn1S(=O)(=O)c1ccc(C)cc1)-c1ccccc1

InChI Key: InChIKey=XFUBAMRHINDIFQ-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 46993   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MCOLN3 protein (Homo sapiens (Human))	BDBM46993 (5-methyl-3-phenyl-4-(2-tosylpyrazol-3-yl)isoxazole...) Show SMILES Cc1onc(c1-c1ccnn1S(=O)(=O)c1ccc(C)cc1)-c1ccccc1 |(6.9,-1.41,;7.81,-.16,;9.35,-.16,;9.82,1.3,;8.58,2.21,;7.33,1.3,;5.87,1.78,;5.39,3.24,;3.85,3.24,;3.37,1.78,;4.62,.87,;4.62,-.67,;6.16,-.67,;3.08,-.67,;4.62,-2.21,;3.29,-2.98,;3.29,-4.52,;4.62,-5.29,;4.62,-6.83,;5.95,-4.52,;5.95,-2.98,;8.58,3.75,;9.91,4.52,;9.91,6.06,;8.58,6.83,;7.24,6.06,;7.24,4.52,)| Show InChI InChI=1S/C20H17N3O3S/c1-14-8-10-17(11-9-14)27(24,25)23-18(12-13-21-23)19-15(2)26-22-20(19)16-6-4-3-5-7-16/h3-13H,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	819	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q21834W4
					More data for this Ligand-Target Pair
transient receptor potential cation channel, subfamily N, member 1 (Danio rerio)	BDBM46993 (5-methyl-3-phenyl-4-(2-tosylpyrazol-3-yl)isoxazole...) Show SMILES Cc1onc(c1-c1ccnn1S(=O)(=O)c1ccc(C)cc1)-c1ccccc1 |(6.9,-1.41,;7.81,-.16,;9.35,-.16,;9.82,1.3,;8.58,2.21,;7.33,1.3,;5.87,1.78,;5.39,3.24,;3.85,3.24,;3.37,1.78,;4.62,.87,;4.62,-.67,;6.16,-.67,;3.08,-.67,;4.62,-2.21,;3.29,-2.98,;3.29,-4.52,;4.62,-5.29,;4.62,-6.83,;5.95,-4.52,;5.95,-2.98,;8.58,3.75,;9.91,4.52,;9.91,6.06,;8.58,6.83,;7.24,6.06,;7.24,4.52,)| Show InChI InChI=1S/C20H17N3O3S/c1-14-8-10-17(11-9-14)27(24,25)23-18(12-13-21-23)19-15(2)26-22-20(19)16-6-4-3-5-7-16/h3-13H,1-2H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>2.99E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q27D2SM8
					More data for this Ligand-Target Pair
MCOLN3 protein (Homo sapiens (Human))	BDBM46993 (5-methyl-3-phenyl-4-(2-tosylpyrazol-3-yl)isoxazole...) Show SMILES Cc1onc(c1-c1ccnn1S(=O)(=O)c1ccc(C)cc1)-c1ccccc1 |(6.9,-1.41,;7.81,-.16,;9.35,-.16,;9.82,1.3,;8.58,2.21,;7.33,1.3,;5.87,1.78,;5.39,3.24,;3.85,3.24,;3.37,1.78,;4.62,.87,;4.62,-.67,;6.16,-.67,;3.08,-.67,;4.62,-2.21,;3.29,-2.98,;3.29,-4.52,;4.62,-5.29,;4.62,-6.83,;5.95,-4.52,;5.95,-2.98,;8.58,3.75,;9.91,4.52,;9.91,6.06,;8.58,6.83,;7.24,6.06,;7.24,4.52,)| Show InChI InChI=1S/C20H17N3O3S/c1-14-8-10-17(11-9-14)27(24,25)23-18(12-13-21-23)19-15(2)26-22-20(19)16-6-4-3-5-7-16/h3-13H,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2W66J7S
					More data for this Ligand-Target Pair
transient receptor potential cation channel, subfamily N, member 1 (Danio rerio)	BDBM46993 (5-methyl-3-phenyl-4-(2-tosylpyrazol-3-yl)isoxazole...) Show SMILES Cc1onc(c1-c1ccnn1S(=O)(=O)c1ccc(C)cc1)-c1ccccc1 |(6.9,-1.41,;7.81,-.16,;9.35,-.16,;9.82,1.3,;8.58,2.21,;7.33,1.3,;5.87,1.78,;5.39,3.24,;3.85,3.24,;3.37,1.78,;4.62,.87,;4.62,-.67,;6.16,-.67,;3.08,-.67,;4.62,-2.21,;3.29,-2.98,;3.29,-4.52,;4.62,-5.29,;4.62,-6.83,;5.95,-4.52,;5.95,-2.98,;8.58,3.75,;9.91,4.52,;9.91,6.06,;8.58,6.83,;7.24,6.06,;7.24,4.52,)| Show InChI InChI=1S/C20H17N3O3S/c1-14-8-10-17(11-9-14)27(24,25)23-18(12-13-21-23)19-15(2)26-22-20(19)16-6-4-3-5-7-16/h3-13H,1-2H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	2.99E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2Z60MG3
					More data for this Ligand-Target Pair