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SMILES: CCn1ccn(Cc2cc(cc(c2)-c2cccnc2C(F)(F)F)C(=O)N[C@@H](C2CC2)c2ccc(F)c(C)c2)c1=N

InChI Key: InChIKey=MCGFPQFQBSHHTF-SANMLTNESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 473281   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM473281
PNG
(US10844044, Example 114)
Show SMILES CCn1ccn(Cc2cc(cc(c2)-c2cccnc2C(F)(F)F)C(=O)N[C@@H](C2CC2)c2ccc(F)c(C)c2)c1=N |r|
Show InChI InChI=1S/C30H29F4N5O/c1-3-38-11-12-39(29(38)35)17-19-14-22(24-5-4-10-36-27(24)30(32,33)34)16-23(15-19)28(40)37-26(20-6-7-20)21-8-9-25(31)18(2)13-21/h4-5,8-16,20,26,35H,3,6-7,17H2,1-2H3,(H,37,40)/t26-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
<0.100n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...

US Patent US10844044 (2020)

More data for this
Ligand-Target Pair