BDBM476288 US10874675, Example 26

SMILES: CC(C)Cn1c2nc(COc3cccc4cccnc34)c(CCCCCO)nc2c(=O)n(C)c1=O

InChI Key: InChIKey=KIFPNZPBSRAVOS-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476288   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Malignant T-cell-amplified sequence 1 (Homo sapiens (human))	BDBM476288 (US10874675, Example 26) Show SMILES CC(C)Cn1c2nc(COc3cccc4cccnc34)c(CCCCCO)nc2c(=O)n(C)c1=O Show InChI InChI=1S/C26H31N5O4/c1-17(2)15-31-24-23(25(33)30(3)26(31)34)28-19(11-5-4-6-14-32)20(29-24)16-35-21-12-7-9-18-10-8-13-27-22(18)21/h7-10,12-13,17,32H,4-6,11,14-16H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<500	n/a	n/a	n/a	n/a
THE SCRIPPS RESEARCH INSTITUTE US Patent					Assay Description Specific Examples of compounds of the invention, with estimated EC50 values determined using an MTT assay for 4-day viability of Raji (Burkitt's)...				US Patent US10874675 (2020)
					More data for this Ligand-Target Pair