BindingDB logo
myBDB logout

null

SMILES: Oc1c(CNc2ccc(cc2)C#CC#Cc2ccc(cc2)C(=O)N2CCOCC2)nc[nH]c1=O

InChI Key: InChIKey=CQRYQRHXYOAPDM-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476342   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
UDP-3-O-acyl-N-acetylglucosamine deacetylase


()		BDBM476342
PNG
(US10875832, Compound 97)
Show SMILES Oc1c(CNc2ccc(cc2)C#CC#Cc2ccc(cc2)C(=O)N2CCOCC2)nc[nH]c1=O
Show InChI InChI=1S/C26H22N4O4/c31-24-23(28-18-29-25(24)32)17-27-22-11-7-20(8-12-22)4-2-1-3-19-5-9-21(10-6-19)26(33)30-13-15-34-16-14-30/h5-12,18,27,31H,13-17H2,(H,28,29,32)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



FORGE THERAPEUTICS, INC.

US Patent


Assay Description
LpxC inhibition assays were performed using liquid chromatography with tandem mass spectrometry. Assays were performed, in duplicate, in opaque, 96-w...

US Patent US10875832 (2020)

More data for this
Ligand-Target Pair