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SMILES: Oc1c(CNc2ccc(cc2)C#Cc2ccc(CN3CCOCC3)cc2)nc[nH]c1=O

InChI Key: InChIKey=HMOWCTCXRDMZQQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476343   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
UDP-3-O-acyl-N-acetylglucosamine deacetylase


()		BDBM476343
PNG
(US10875832, Compound 98)
Show SMILES Oc1c(CNc2ccc(cc2)C#Cc2ccc(CN3CCOCC3)cc2)nc[nH]c1=O
Show InChI InChI=1S/C24H24N4O3/c29-23-22(26-17-27-24(23)30)15-25-21-9-7-19(8-10-21)2-1-18-3-5-20(6-4-18)16-28-11-13-31-14-12-28/h3-10,17,25,29H,11-16H2,(H,26,27,30)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



FORGE THERAPEUTICS, INC.

US Patent


Assay Description
LpxC inhibition assays were performed using liquid chromatography with tandem mass spectrometry. Assays were performed, in duplicate, in opaque, 96-w...

US Patent US10875832 (2020)

More data for this
Ligand-Target Pair