BDBM47728 (2E)-3-(2-chloroanilino)-2-(3,3-dimethyl-2,4-dihydroisoquinolin-1-ylidene)-3-keto-propionic acid ethyl ester::(2E)-3-(2-chloroanilino)-2-(3,3-dimethyl-2,4-dihydroisoquinolin-1-ylidene)-3-oxopropanoic acid ethyl ester::MLS000579063::SMR000186652::cid_2857584::ethyl (2E)-3-(2-chloroanilino)-2-(3,3-dimethyl-2,4-dihydroisoquinolin-1-ylidene)-3-oxopropanoate::ethyl (2E)-3-[(2-chlorophenyl)amino]-2-(3,3-dimethyl-2,4-dihydroisoquinolin-1-ylidene)-3-oxidanylidene-propanoate::ethyl 3-[(2-chlorophenyl)amino]-2-(3,3-dimethyl-3,4-dihydro-1(2H)-isoquinolinylidene)-3-oxopropanoate

SMILES: CCOC(=O)C(C(=O)Nc1ccccc1Cl)C1=NC(C)(C)Cc2ccccc12

InChI Key: InChIKey=VWSLUTFHLASBAD-UHFFFAOYSA-N

Data: 5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 47728   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RGS7 (Homo sapiens (Human))	BDBM47728 ((2E)-3-(2-chloroanilino)-2-(3,3-dimethyl-2,4-dihyd...) Show SMILES CCOC(=O)C(C(=O)Nc1ccccc1Cl)C1=NC(C)(C)Cc2ccccc12 |t:17| Show InChI InChI=1S/C22H23ClN2O3/c1-4-28-21(27)18(20(26)24-17-12-8-7-11-16(17)23)19-15-10-6-5-9-14(15)13-22(2,3)25-19/h5-12,18H,4,13H2,1-3H3,(H,24,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2PV6HS7
					More data for this Ligand-Target Pair
G protein signalling regulator 19 (Homo sapiens (Human))	BDBM47728 ((2E)-3-(2-chloroanilino)-2-(3,3-dimethyl-2,4-dihyd...) Show SMILES CCOC(=O)C(C(=O)Nc1ccccc1Cl)C1=NC(C)(C)Cc2ccccc12 |t:17| Show InChI InChI=1S/C22H23ClN2O3/c1-4-28-21(27)18(20(26)24-17-12-8-7-11-16(17)23)19-15-10-6-5-9-14(15)13-22(2,3)25-19/h5-12,18H,4,13H2,1-3H3,(H,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2K35S27
					More data for this Ligand-Target Pair
regulator of G-protein signaling 4 (Homo sapiens (Human))	BDBM47728 ((2E)-3-(2-chloroanilino)-2-(3,3-dimethyl-2,4-dihyd...) Show SMILES CCOC(=O)C(C(=O)Nc1ccccc1Cl)C1=NC(C)(C)Cc2ccccc12 |t:17| Show InChI InChI=1S/C22H23ClN2O3/c1-4-28-21(27)18(20(26)24-17-12-8-7-11-16(17)23)19-15-10-6-5-9-14(15)13-22(2,3)25-19/h5-12,18H,4,13H2,1-3H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2F76B0G
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 8 (Homo sapiens (Human))	BDBM47728 ((2E)-3-(2-chloroanilino)-2-(3,3-dimethyl-2,4-dihyd...) Show SMILES CCOC(=O)C(C(=O)Nc1ccccc1Cl)C1=NC(C)(C)Cc2ccccc12 |t:17| Show InChI InChI=1S/C22H23ClN2O3/c1-4-28-21(27)18(20(26)24-17-12-8-7-11-16(17)23)19-15-10-6-5-9-14(15)13-22(2,3)25-19/h5-12,18H,4,13H2,1-3H3,(H,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2TM78JD
					More data for this Ligand-Target Pair
regulator of G-protein signalling 16 (Homo sapiens (Human))	BDBM47728 ((2E)-3-(2-chloroanilino)-2-(3,3-dimethyl-2,4-dihyd...) Show SMILES CCOC(=O)C(C(=O)Nc1ccccc1Cl)C1=NC(C)(C)Cc2ccccc12 |t:17| Show InChI InChI=1S/C22H23ClN2O3/c1-4-28-21(27)18(20(26)24-17-12-8-7-11-16(17)23)19-15-10-6-5-9-14(15)13-22(2,3)25-19/h5-12,18H,4,13H2,1-3H3,(H,24,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2FB51BW
					More data for this Ligand-Target Pair