BDBM47738 2-(4-keto-1-phenyl-pyrazolo[3,4-d]pyrimidin-5-yl)-N-(4-morpholinosulfonylphenyl)acetamide::MLS000553495::N-(4-morpholin-4-ylsulfonylphenyl)-2-(4-oxidanylidene-1-phenyl-pyrazolo[3,4-d]pyrimidin-5-yl)ethanamide::N-(4-morpholin-4-ylsulfonylphenyl)-2-(4-oxo-1-phenylpyrazolo[3,4-d]pyrimidin-5-yl)acetamide::N-[4-(4-morpholinylsulfonyl)phenyl]-2-(4-oxo-1-phenyl-5-pyrazolo[3,4-d]pyrimidinyl)acetamide::N-[4-(Morpholine-4-sulfonyl)-phenyl]-2-(4-oxo-1-phenyl-1,4-dihydro-pyrazolo[3,4-d]pyrimidin-5-yl)-acetamide::SMR000172350::cid_1088465

SMILES: O=C(Cn1cnc2n(ncc2c1=O)-c1ccccc1)Nc1ccc(cc1)S(=O)(=O)N1CCOCC1

InChI Key: InChIKey=GFKIHACFFOITCC-UHFFFAOYSA-N

Data: 6 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 47738   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RGS7 (Homo sapiens (Human))	BDBM47738 (2-(4-keto-1-phenyl-pyrazolo[3,4-d]pyrimidin-5-yl)-...) Show SMILES O=C(Cn1cnc2n(ncc2c1=O)-c1ccccc1)Nc1ccc(cc1)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C23H22N6O5S/c30-21(26-17-6-8-19(9-7-17)35(32,33)28-10-12-34-13-11-28)15-27-16-24-22-20(23(27)31)14-25-29(22)18-4-2-1-3-5-18/h1-9,14,16H,10-13,15H2,(H,26,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2PV6HS7
					More data for this Ligand-Target Pair
G protein signalling regulator 19 (Homo sapiens (Human))	BDBM47738 (2-(4-keto-1-phenyl-pyrazolo[3,4-d]pyrimidin-5-yl)-...) Show SMILES O=C(Cn1cnc2n(ncc2c1=O)-c1ccccc1)Nc1ccc(cc1)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C23H22N6O5S/c30-21(26-17-6-8-19(9-7-17)35(32,33)28-10-12-34-13-11-28)15-27-16-24-22-20(23(27)31)14-25-29(22)18-4-2-1-3-5-18/h1-9,14,16H,10-13,15H2,(H,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2K35S27
					More data for this Ligand-Target Pair
cardiac alpha tropomyosin (Sus scrofa)	BDBM47738 (2-(4-keto-1-phenyl-pyrazolo[3,4-d]pyrimidin-5-yl)-...) Show SMILES O=C(Cn1cnc2n(ncc2c1=O)-c1ccccc1)Nc1ccc(cc1)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C23H22N6O5S/c30-21(26-17-6-8-19(9-7-17)35(32,33)28-10-12-34-13-11-28)15-27-16-24-22-20(23(27)31)14-25-29(22)18-4-2-1-3-5-18/h1-9,14,16H,10-13,15H2,(H,26,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>7.15E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q21N7ZKB
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 8 (Homo sapiens (Human))	BDBM47738 (2-(4-keto-1-phenyl-pyrazolo[3,4-d]pyrimidin-5-yl)-...) Show SMILES O=C(Cn1cnc2n(ncc2c1=O)-c1ccccc1)Nc1ccc(cc1)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C23H22N6O5S/c30-21(26-17-6-8-19(9-7-17)35(32,33)28-10-12-34-13-11-28)15-27-16-24-22-20(23(27)31)14-25-29(22)18-4-2-1-3-5-18/h1-9,14,16H,10-13,15H2,(H,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2TM78JD
					More data for this Ligand-Target Pair
regulator of G-protein signaling 4 (Homo sapiens (Human))	BDBM47738 (2-(4-keto-1-phenyl-pyrazolo[3,4-d]pyrimidin-5-yl)-...) Show SMILES O=C(Cn1cnc2n(ncc2c1=O)-c1ccccc1)Nc1ccc(cc1)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C23H22N6O5S/c30-21(26-17-6-8-19(9-7-17)35(32,33)28-10-12-34-13-11-28)15-27-16-24-22-20(23(27)31)14-25-29(22)18-4-2-1-3-5-18/h1-9,14,16H,10-13,15H2,(H,26,30)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2F76B0G
					More data for this Ligand-Target Pair
regulator of G-protein signalling 16 (Homo sapiens (Human))	BDBM47738 (2-(4-keto-1-phenyl-pyrazolo[3,4-d]pyrimidin-5-yl)-...) Show SMILES O=C(Cn1cnc2n(ncc2c1=O)-c1ccccc1)Nc1ccc(cc1)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C23H22N6O5S/c30-21(26-17-6-8-19(9-7-17)35(32,33)28-10-12-34-13-11-28)15-27-16-24-22-20(23(27)31)14-25-29(22)18-4-2-1-3-5-18/h1-9,14,16H,10-13,15H2,(H,26,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2FB51BW
					More data for this Ligand-Target Pair