null
SMILES: CCn1c(nc2cc(cc(-c3ccn[nH]3)c12)C(=O)Nc1ccc(OC(F)(F)Cl)cc1)[C@H](C)O
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM477839 (US10889571, Example 187) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.330 | n/a | n/a | n/a | n/a | n/a | n/a |
Terns, Inc. US Patent | Assay Description ABL1 WT protein (64-515aa) containing an N-terminal His tag was produced by co-expression with YopH in Sf9 insect cells. Cells were harvested by cent... | US Patent US10889571 (2021) BindingDB Entry DOI: 10.7270/Q27S7RW4 | |||||||||||
More data for this Ligand-Target Pair |