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SMILES: OC(=O)CC[C@H](NC(=O)N[C@@H](Cc1ccc(NC(=O)Nc2ccc(cc2)-n2cc(CCCF)nn2)cc1)C(O)=O)C(O)=O

InChI Key: InChIKey=MTIBIRURCCTBCU-VXKWHMMOSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 479421   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate carboxypeptidase 2


(Homo sapiens (Human))		BDBM479421
PNG
(US10894807, ID P212)
Show SMILES OC(=O)CC[C@H](NC(=O)N[C@@H](Cc1ccc(NC(=O)Nc2ccc(cc2)-n2cc(CCCF)nn2)cc1)C(O)=O)C(O)=O |r|
Show InChI InChI=1S/C27H30FN7O8/c28-13-1-2-19-15-35(34-33-19)20-9-7-18(8-10-20)30-26(42)29-17-5-3-16(4-6-17)14-22(25(40)41)32-27(43)31-21(24(38)39)11-12-23(36)37/h3-10,15,21-22H,1-2,11-14H2,(H,36,37)(H,38,39)(H,40,41)(H2,29,30,42)(H2,31,32,43)/t21-,22-/m0/s1
PDB
MMDB

KEGG

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PC cid
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US Patent
 3.10n/an/an/an/an/an/an/an/a



Siemens Medical Solutions USA, Inc.

US Patent


Assay Description
The inhibitory activity of all compounds was determined using a fluorescent assay of human PSMA activity. The enzyme used in the assay was purchased ...

US Patent US10894807 (2021)

More data for this
Ligand-Target Pair