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SMILES: OC(=O)CC[C@H](NC(=O)N[C@@H](Cc1ccc(NC(=O)N2CCN(CC2)C(=O)Cn2cc(CCCF)nn2)cc1)C(O)=O)C(O)=O

InChI Key: InChIKey=SSXKMUKMBFRGDD-SFTDATJTSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 479430   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate carboxypeptidase 2


(Homo sapiens (Human))		BDBM479430
PNG
(US10894807, ID P237)
Show SMILES OC(=O)CC[C@H](NC(=O)N[C@@H](Cc1ccc(NC(=O)N2CCN(CC2)C(=O)Cn2cc(CCCF)nn2)cc1)C(O)=O)C(O)=O |r|
Show InChI InChI=1S/C27H35FN8O9/c28-9-1-2-19-15-36(33-32-19)16-22(37)34-10-12-35(13-11-34)27(45)29-18-5-3-17(4-6-18)14-21(25(42)43)31-26(44)30-20(24(40)41)7-8-23(38)39/h3-6,15,20-21H,1-2,7-14,16H2,(H,29,45)(H,38,39)(H,40,41)(H,42,43)(H2,30,31,44)/t20-,21-/m0/s1
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KEGG

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PC cid
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US Patent
 3.80n/an/an/an/an/an/an/an/a



Siemens Medical Solutions USA, Inc.

US Patent


Assay Description
The inhibitory activity of all compounds was determined using a fluorescent assay of human PSMA activity. The enzyme used in the assay was purchased ...

US Patent US10894807 (2021)

More data for this
Ligand-Target Pair