BDBM4795 4-Anilinopyrido[3,4-d]pyrimidine 22::N-[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-N-[3-(4-morpholinyl)propyl]acrylamide::N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}-N-[3-(morpholin-4-yl)propyl]prop-2-enamide

SMILES: Brc1cccc(Nc2ncnc3cnc(cc23)N(CCCN2CCOCC2)C(=O)C=C)c1

InChI Key: InChIKey=OCBRGIXVRJXGMM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4795   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM4795 (4-Anilinopyrido[3,4-d]pyrimidine 22 | N-[4-(3-Brom...) Show SMILES Brc1cccc(Nc2ncnc3cnc(cc23)N(CCCN2CCOCC2)C(=O)C=C)c1 Show InChI InChI=1S/C23H25BrN6O2/c1-2-22(31)30(8-4-7-29-9-11-32-12-10-29)21-14-19-20(15-25-21)26-16-27-23(19)28-18-6-3-5-17(24)13-18/h2-3,5-6,13-16H,1,4,7-12H2,(H,26,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...				J Med Chem 44: 429-40 (2001) Article DOI: 10.1021/jm000372i BindingDB Entry DOI: 10.7270/Q2HX19WB
					More data for this Ligand-Target Pair