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BDBM48060 3-amino-4-methyl-N-p-anisyl-6-(2-pyrrolidinoethoxy)thieno[2,3-b]pyridine-2-carboxamide::3-amino-N-[(4-methoxyphenyl)methyl]-4-methyl-6-(2-pyrrolidin-1-ylethoxy)thieno[2,3-b]pyridine-2-carboxamide::3-amino-N-[(4-methoxyphenyl)methyl]-4-methyl-6-[2-(1-pyrrolidinyl)ethoxy]-2-thieno[2,3-b]pyridinecarboxamide::3-azanyl-N-[(4-methoxyphenyl)methyl]-4-methyl-6-(2-pyrrolidin-1-ylethoxy)thieno[2,3-b]pyridine-2-carboxamide::VU0152120::cid_45142472

SMILES: COc1ccc(CNC(=O)c2sc3nc(OCCN4CCCC4)cc(C)c3c2N)cc1

InChI Key: InChIKey=SGGKLGYCZZOJSC-UHFFFAOYSA-N

Data: 1 EC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 48060   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M4


(RAT)		BDBM48060
PNG
(3-amino-4-methyl-N-p-anisyl-6-(2-pyrrolidinoethoxy...)
Show SMILES COc1ccc(CNC(=O)c2sc3nc(OCCN4CCCC4)cc(C)c3c2N)cc1
Show InChI InChI=1S/C23H28N4O3S/c1-15-13-18(30-12-11-27-9-3-4-10-27)26-23-19(15)20(24)21(31-23)22(28)25-14-16-5-7-17(29-2)8-6-16/h5-8,13H,3-4,9-12,14,24H2,1-2H3,(H,25,28)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
PCBioAssay
n/an/an/an/a 8.24E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University Grant Title: Discovery of a Highly Selective in vitro and in vivo...

PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2251GKR
More data for this
Ligand-Target Pair