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BDBM48061 3-amino-4-methyl-6-[(1-methyl-3-piperidyl)methoxy]-N-p-anisyl-thieno[2,3-b]pyridine-2-carboxamide::3-amino-N-[(4-methoxyphenyl)methyl]-4-methyl-6-[(1-methyl-3-piperidinyl)methoxy]-2-thieno[2,3-b]pyridinecarboxamide::3-amino-N-[(4-methoxyphenyl)methyl]-4-methyl-6-[(1-methylpiperidin-3-yl)methoxy]thieno[2,3-b]pyridine-2-carboxamide::3-azanyl-N-[(4-methoxyphenyl)methyl]-4-methyl-6-[(1-methylpiperidin-3-yl)methoxy]thieno[2,3-b]pyridine-2-carboxamide::VU0152121::cid_45142473

SMILES: COc1ccc(CNC(=O)c2sc3nc(OCC4CCCN(C)C4)cc(C)c3c2N)cc1

InChI Key: InChIKey=CIBXLIIYKIADDU-UHFFFAOYSA-N

Data: 1 EC50

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 48061   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M4


(RAT)		BDBM48061
PNG
(3-amino-4-methyl-6-[(1-methyl-3-piperidyl)methoxy]...)
Show SMILES COc1ccc(CNC(=O)c2sc3nc(OCC4CCCN(C)C4)cc(C)c3c2N)cc1
Show InChI InChI=1S/C24H30N4O3S/c1-15-11-19(31-14-17-5-4-10-28(2)13-17)27-24-20(15)21(25)22(32-24)23(29)26-12-16-6-8-18(30-3)9-7-16/h6-9,11,17H,4-5,10,12-14,25H2,1-3H3,(H,26,29)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
PCBioAssay
n/an/an/an/a 1.00E+4n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University Grant Title: Discovery of a Highly Selective in vitro and in vivo...

PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2251GKR
More data for this
Ligand-Target Pair