BDBM481158 US10906900, Reference 25b

SMILES: CN(C)c1ccc(cc1)C#Cc1cc2ccc(nc2[nH]1)-c1ccsc1

InChI Key: InChIKey=SPYYWCDGZNJHNH-UHFFFAOYSA-N

Data: 2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 481158   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-synuclein (Homo sapiens (Human))	BDBM481158 (US10906900, Reference 25b) Show SMILES CN(C)c1ccc(cc1)C#Cc1cc2ccc(nc2[nH]1)-c1ccsc1 Show InChI InChI=1S/C21H17N3S/c1-24(2)19-8-4-15(5-9-19)3-7-18-13-16-6-10-20(23-21(16)22-18)17-11-12-25-14-17/h4-6,8-14H,1-2H3,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.730	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021)
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein [1-42] (Homo sapiens (Human))	BDBM481158 (US10906900, Reference 25b) Show SMILES CN(C)c1ccc(cc1)C#Cc1cc2ccc(nc2[nH]1)-c1ccsc1 Show InChI InChI=1S/C21H17N3S/c1-24(2)19-8-4-15(5-9-19)3-7-18-13-16-6-10-20(23-21(16)22-18)17-11-12-25-14-17/h4-6,8-14H,1-2H3,(H,22,23)	MMDB B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	4.27	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021)
					More data for this Ligand-Target Pair