BindingDB logo
myBDB logout

null

SMILES: Cc1ccc(CN(CC2CCNCC2)S(=O)(=O)c2ccc(cc2)S(=O)(=O)N(Cc2ccc(Cl)cc2)C2CCCC2)cc1N

InChI Key: InChIKey=WWHIENFMLHIZLU-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481608   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta


(Homo sapiens (Human))		BDBM481608
PNG
(US10913710, Compound 23)
Show SMILES Cc1ccc(CN(CC2CCNCC2)S(=O)(=O)c2ccc(cc2)S(=O)(=O)N(Cc2ccc(Cl)cc2)C2CCCC2)cc1N
Show InChI InChI=1S/C32H41ClN4O4S2/c1-24-6-7-27(20-32(24)34)22-36(21-26-16-18-35-19-17-26)42(38,39)30-12-14-31(15-13-30)43(40,41)37(29-4-2-3-5-29)23-25-8-10-28(33)11-9-25/h6-15,20,26,29,35H,2-5,16-19,21-23,34H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 16n/an/an/an/an/a



Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V

US Patent


Assay Description
Binding to PDEδ was validated and quantified by means of a displacement assay employing a fluorescent-tagged analog of the HMG-CoA reductase inh...

US Patent US10913710 (2021)

More data for this
Ligand-Target Pair