null

SMILES: C[C@@H](O)[C@H](NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CCC[C@@H](O)C3)c2C)cc1OCc1cncc(c1)C#N)C(O)=O

InChI Key: InChIKey=AVKPYQULGQWNAD-IHAFIETQSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 482313   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM482313 (US10919852, Compound TABLE 1.12 | US11708326, Comp...) Show SMILES C[C@@H](O)[C@H](NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CCC[C@@H](O)C3)c2C)cc1OCc1cncc(c1)C#N)C(O)=O |r| Show InChI InChI=1S/C42H47ClN4O7/c1-26-32(8-4-11-37(26)52-16-6-15-47-14-5-7-31(49)24-47)33-9-3-10-35-34(33)12-13-38(35)54-40-19-39(53-25-29-17-28(20-44)21-45-22-29)30(18-36(40)43)23-46-41(27(2)48)42(50)51/h3-4,8-11,17-19,21-22,27,31,38,41,46,48-49H,5-7,12-16,23-25H2,1-2H3,(H,50,51)/t27-,31-,38+,41+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N56DJ
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482313 (US10919852, Compound TABLE 1.12 | US11708326, Comp...) Show SMILES C[C@@H](O)[C@H](NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CCC[C@@H](O)C3)c2C)cc1OCc1cncc(c1)C#N)C(O)=O |r| Show InChI InChI=1S/C42H47ClN4O7/c1-26-32(8-4-11-37(26)52-16-6-15-47-14-5-7-31(49)24-47)33-9-3-10-35-34(33)12-13-38(35)54-40-19-39(53-25-29-17-28(20-44)21-45-22-29)30(18-36(40)43)23-46-41(27(2)48)42(50)51/h3-4,8-11,17-19,21-22,27,31,38,41,46,48-49H,5-7,12-16,23-25H2,1-2H3,(H,50,51)/t27-,31-,38+,41+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair