BDBM483555 US10927079, Compound 21

SMILES: Cc1cc(NC(=O)N[C@H]2CCC(C)(C)c3ccccc23)c(nc1-c1cnc(nc1)C(C)(C)O)-c1ccccc1

InChI Key: InChIKey=FDQAMDYWLLXKLK-VWLOTQADSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 483555   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM483555 (US10927079, Compound 21) Show SMILES Cc1cc(NC(=O)N[C@H]2CCC(C)(C)c3ccccc23)c(nc1-c1cnc(nc1)C(C)(C)O)-c1ccccc1 Show InChI InChI=1S/C32H35N5O2/c1-20-17-26(36-30(38)35-25-15-16-31(2,3)24-14-10-9-13-23(24)25)28(21-11-7-6-8-12-21)37-27(20)22-18-33-29(34-19-22)32(4,5)39/h6-14,17-19,25,39H,15-16H2,1-5H3,(H2,35,36,38)/t25-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.100	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10927079 (2021)
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