BDBM483567 US10927079, Compound 33

SMILES: COCc1ccc2c(c1)[C@@H](NC(=O)Nc1cc(C)cnc1C1CCOCC1)[C@H](O)CC2(C)C

InChI Key: InChIKey=ABKQVBISCAPRHO-ISKFKSNPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 483567   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM483567 (US10927079, Compound 33) Show SMILES COCc1ccc2c(c1)[C@@H](NC(=O)Nc1cc(C)cnc1C1CCOCC1)[C@H](O)CC2(C)C Show InChI InChI=1S/C26H35N3O4/c1-16-11-21(23(27-14-16)18-7-9-33-10-8-18)28-25(31)29-24-19-12-17(15-32-4)5-6-20(19)26(2,3)13-22(24)30/h5-6,11-12,14,18,22,24,30H,7-10,13,15H2,1-4H3,(H2,28,29,31)/t22-,24-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.100	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10927079 (2021)
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