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SMILES: CCCCNCc1ccc(cc1)-c1cccc(c1)S(=O)(=O)N1CCC2(C[C@@H](CO2)NC[C@H](O)COc2cccc(c2)S(=O)(=O)C2(CO)CC2)CC1

InChI Key: InChIKey=CZGOTIBAUNXPDM-LQJZCPKCSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484066   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM484066
PNG
((S)-1-((S)-8-(4'- ((butylamino)methyl) biphenyl-3-...)
Show SMILES CCCCNCc1ccc(cc1)-c1cccc(c1)S(=O)(=O)N1CCC2(C[C@@H](CO2)NC[C@H](O)COc2cccc(c2)S(=O)(=O)C2(CO)CC2)CC1 |r|
Show InChI InChI=1S/C38H51N3O8S2/c1-2-3-18-39-24-29-10-12-30(13-11-29)31-6-4-9-36(21-31)51(46,47)41-19-16-37(17-20-41)23-32(26-49-37)40-25-33(43)27-48-34-7-5-8-35(22-34)50(44,45)38(28-42)14-15-38/h4-13,21-22,32-33,39-40,42-43H,2-3,14-20,23-28H2,1H3/t32-,33-/m0/s1
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US Patent
n/an/a 1.84E+4n/an/an/an/an/an/a



Arena Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...

US Patent US10927123 (2021)

More data for this
Ligand-Target Pair