null
SMILES: CS(=O)(=O)c1cccc(OC[C@@H](O)CN[C@H]2COC3(C2)CCN(CC3)S(=O)(=O)c2cnc3cc[nH]c3c2)c1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-3 adrenergic receptor (Homo sapiens (Human)) | BDBM484073 ((S)-1-((R)-8-(1H- pyrrolo[3,2-b]pyridin-6- ylsulfo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.78E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals, Inc. US Patent | Assay Description Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass... | US Patent US10927123 (2021) BindingDB Entry DOI: 10.7270/Q2D221QM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-3 adrenergic receptor (Homo sapiens (Human)) | BDBM484073 ((S)-1-((R)-8-(1H- pyrrolo[3,2-b]pyridin-6- ylsulfo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals, Inc. US Patent | Assay Description Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass... | US Patent US10927123 (2021) BindingDB Entry DOI: 10.7270/Q2D221QM | |||||||||||
More data for this Ligand-Target Pair |