BDBM484086 (S)-4-ethyl-9-isopentyl-2-methyl-1-oxa- 4,9-diazaspiro[5.5]undecan-3-one::US10927128, Example 52::US10927128, Example 7

SMILES: CCN1CC2(CCN(CCC(C)C)CC2)O[C@@H](C)C1=O

InChI Key: InChIKey=HZLZOCCUGODKEE-AWEZNQCLSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 484086   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma-1 (Homo sapiens (Human))	BDBM484086 ((S)-4-ethyl-9-isopentyl-2-methyl-1-oxa- 4,9-diazas...) Show SMILES CCN1CC2(CCN(CCC(C)C)CC2)O[C@@H](C)C1=O |r| Show InChI InChI=1S/C16H30N2O2/c1-5-18-12-16(20-14(4)15(18)19)7-10-17(11-8-16)9-6-13(2)3/h13-14H,5-12H2,1-4H3/t14-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021)
					More data for this Ligand-Target Pair
Sigma-1 (Homo sapiens (Human))	BDBM484086 ((S)-4-ethyl-9-isopentyl-2-methyl-1-oxa- 4,9-diazas...) Show SMILES CCN1CC2(CCN(CCC(C)C)CC2)O[C@@H](C)C1=O |r| Show InChI InChI=1S/C16H30N2O2/c1-5-18-12-16(20-14(4)15(18)19)7-10-17(11-8-16)9-6-13(2)3/h13-14H,5-12H2,1-4H3/t14-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021)
					More data for this Ligand-Target Pair