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BDBM484102 12-ethyl-8-(3-fluorobenzyl)-4-oxa-8,12- diazadispiro[2.1.5.3]tridecan-13-one::US10927128, Example 23

SMILES: CCN1CC2(CCN(Cc3cccc(F)c3)CC2)OC2(CC2)C1=O

InChI Key: InChIKey=MDGMNIKPWJJRMQ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484102   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sigma-1


(Homo sapiens (Human))		BDBM484102
PNG
(12-ethyl-8-(3-fluorobenzyl)-4-oxa-8,12- diazadispi...)
Show SMILES CCN1CC2(CCN(Cc3cccc(F)c3)CC2)OC2(CC2)C1=O
Show InChI InChI=1S/C19H25FN2O2/c1-2-22-14-18(24-19(6-7-19)17(22)23)8-10-21(11-9-18)13-15-4-3-5-16(20)12-15/h3-5,12H,2,6-11,13-14H2,1H3
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
<100n/an/an/an/an/an/an/an/a



ESTEVE PHARMACEUTICALS. S.A.

US Patent


Assay Description
To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...

US Patent US10927128 (2021)

More data for this
Ligand-Target Pair