BDBM484115 8-(2-(3-fluoropyridin-2-yl)ethyl)-12-isopropyl-4- oxa-8,12-diazadispiro[2.1.5.3]tridecane::US10927128, Example 36

SMILES: CC(C)N1CC2(CC2)OC2(CCN(CCc3ncccc3F)CC2)C1

InChI Key: InChIKey=VNBTXZBMXDJZLO-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484115   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma-1 (Homo sapiens (Human))	BDBM484115 (8-(2-(3-fluoropyridin-2-yl)ethyl)-12-isopropyl-4- ...) Show SMILES CC(C)N1CC2(CC2)OC2(CCN(CCc3ncccc3F)CC2)C1 Show InChI InChI=1S/C20H30FN3O/c1-16(2)24-14-19(6-7-19)25-20(15-24)8-12-23(13-9-20)11-5-18-17(21)4-3-10-22-18/h3-4,10,16H,5-9,11-15H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021)
					More data for this Ligand-Target Pair