BDBM484125 8-(2,5-difluorophenethyl)-12- isobutyl-4-oxa-8,12- diazadispiro[2.1.5.3]tridecane::US10927128, Example 46
SMILES: CC(C)CN1CC2(CC2)OC2(CCN(CCc3cc(F)ccc3F)CC2)C1
InChI Key: InChIKey=JJMDQQZJXJATQE-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sigma-1 (Homo sapiens (Human)) | BDBM484125 (8-(2,5-difluorophenethyl)-12- isobutyl-4-oxa-8,12-...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
ESTEVE PHARMACEUTICALS. S.A. US Patent | Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N... | US Patent US10927128 (2021) | |||||||||||
More data for this Ligand-Target Pair |