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BDBM484126 12-isobutyl-8-(2-(6- methoxypyridin-2-yl)ethyl)-4- oxa-8,12- diazadispiro[2.1.5.3]tridecane::US10927128, Example 47

SMILES: COc1cccc(CCN2CCC3(CC2)CN(CC(C)C)CC2(CC2)O3)n1

InChI Key: InChIKey=VIHULQHCPWVZGX-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484126   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sigma-1


(Homo sapiens (Human))		BDBM484126
PNG
(12-isobutyl-8-(2-(6- methoxypyridin-2-yl)ethyl)-4-...)
Show SMILES COc1cccc(CCN2CCC3(CC2)CN(CC(C)C)CC2(CC2)O3)n1
Show InChI InChI=1S/C22H35N3O2/c1-18(2)15-25-16-21(8-9-21)27-22(17-25)10-13-24(14-11-22)12-7-19-5-4-6-20(23-19)26-3/h4-6,18H,7-17H2,1-3H3
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
<100n/an/an/an/an/an/an/an/a



ESTEVE PHARMACEUTICALS. S.A.

US Patent


Assay Description
To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...

US Patent US10927128 (2021)

More data for this
Ligand-Target Pair