BDBM484146 8-(4-fluorobenzyl)-12-methyl- 4-oxa-8,12- diazadispiro[2.1.5.3]tridecan- 13-one::US10927128, Example 67

SMILES: CN1CC2(CCN(Cc3ccc(F)cc3)CC2)OC2(CC2)C1=O

InChI Key: InChIKey=LXQXEHMARONDLL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484146   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma-1 (Homo sapiens (Human))	BDBM484146 (8-(4-fluorobenzyl)-12-methyl- 4-oxa-8,12- diazadis...) Show SMILES CN1CC2(CCN(Cc3ccc(F)cc3)CC2)OC2(CC2)C1=O Show InChI InChI=1S/C18H23FN2O2/c1-20-13-17(23-18(6-7-18)16(20)22)8-10-21(11-9-17)12-14-2-4-15(19)5-3-14/h2-5H,6-13H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021)
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