BDBM484148 (S)-9-(4-fluorobenzyl)-4- isopropyl-2-methyl-1-oxa-4,9- diazaspiro[5.5]undecan-3- one::US10927128, Example 69

SMILES: CC(C)N1CC2(CCN(Cc3ccc(F)cc3)CC2)O[C@@H](C)C1=O

InChI Key: InChIKey=NIXUOVZXMQSIST-HNNXBMFYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484148   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma-1 (Homo sapiens (Human))	BDBM484148 ((S)-9-(4-fluorobenzyl)-4- isopropyl-2-methyl-1-oxa...) Show SMILES CC(C)N1CC2(CCN(Cc3ccc(F)cc3)CC2)O[C@@H](C)C1=O |r| Show InChI InChI=1S/C19H27FN2O2/c1-14(2)22-13-19(24-15(3)18(22)23)8-10-21(11-9-19)12-16-4-6-17(20)7-5-16/h4-7,14-15H,8-13H2,1-3H3/t15-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021)
					More data for this Ligand-Target Pair