BDBM484154 (R)-4-ethyl-9-(4- methoxybenzyl)-2-methyl-1- oxa-4,9- diazaspiro[5.5]undecan-3- one::US10927128, Example 75

SMILES: CCN1CC2(CCN(Cc3ccc(OC)cc3)CC2)O[C@H](C)C1=O

InChI Key: InChIKey=CYJNKQYHTICWJV-OAHLLOKOSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484154   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma-1 (Homo sapiens (Human))	BDBM484154 ((R)-4-ethyl-9-(4- methoxybenzyl)-2-methyl-1- oxa-4...) Show SMILES CCN1CC2(CCN(Cc3ccc(OC)cc3)CC2)O[C@H](C)C1=O |r| Show InChI InChI=1S/C19H28N2O3/c1-4-21-14-19(24-15(2)18(21)22)9-11-20(12-10-19)13-16-5-7-17(23-3)8-6-16/h5-8,15H,4,9-14H2,1-3H3/t15-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021)
					More data for this Ligand-Target Pair