BDBM484155 9-(4-chlorobenzyl)-4-ethyl- 2,2-dimethyl-1-oxa-4,9- diazaspiro[5.5]undecan-3- one::US10927128, Example 76

SMILES: CCN1CC2(CCN(Cc3ccc(Cl)cc3)CC2)OC(C)(C)C1=O

InChI Key: InChIKey=IZRRBPXRUFUPSZ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484155   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma-1 (Homo sapiens (Human))	BDBM484155 (9-(4-chlorobenzyl)-4-ethyl- 2,2-dimethyl-1-oxa-4,9...) Show SMILES CCN1CC2(CCN(Cc3ccc(Cl)cc3)CC2)OC(C)(C)C1=O Show InChI InChI=1S/C19H27ClN2O2/c1-4-22-14-19(24-18(2,3)17(22)23)9-11-21(12-10-19)13-15-5-7-16(20)8-6-15/h5-8H,4,9-14H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021)
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