BDBM484164 (S)-4-cyclopropyl-9-(4- fluorobenzyl)-2-methyl-1-oxa- 4,9-diazaspiro[5.5]undecan- 3-one::US10927128, Example 85

SMILES: C[C@@H]1OC2(CCN(Cc3ccc(F)cc3)CC2)CN(C2CC2)C1=O

InChI Key: InChIKey=ZOVLTIZCBQXPMP-AWEZNQCLSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484164   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma-1 (Homo sapiens (Human))	BDBM484164 ((S)-4-cyclopropyl-9-(4- fluorobenzyl)-2-methyl-1-o...) Show SMILES C[C@@H]1OC2(CCN(Cc3ccc(F)cc3)CC2)CN(C2CC2)C1=O |r| Show InChI InChI=1S/C19H25FN2O2/c1-14-18(23)22(17-6-7-17)13-19(24-14)8-10-21(11-9-19)12-15-2-4-16(20)5-3-15/h2-5,14,17H,6-13H2,1H3/t14-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021)
					More data for this Ligand-Target Pair