BDBM484165 (S)-9-benzyl-4-cyclopropyl-2- methyl-1-oxa-4,9- diazaspiro[5.5]undecan-3- one::US10927128, Example 86

SMILES: C[C@@H]1OC2(CCN(Cc3ccccc3)CC2)CN(C2CC2)C1=O

InChI Key: InChIKey=IOKHWAWASZFNGU-HNNXBMFYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484165   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma-1 (Homo sapiens (Human))	BDBM484165 ((S)-9-benzyl-4-cyclopropyl-2- methyl-1-oxa-4,9- di...) Show SMILES C[C@@H]1OC2(CCN(Cc3ccccc3)CC2)CN(C2CC2)C1=O |r| Show InChI InChI=1S/C19H26N2O2/c1-15-18(22)21(17-7-8-17)14-19(23-15)9-11-20(12-10-19)13-16-5-3-2-4-6-16/h2-6,15,17H,7-14H2,1H3/t15-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021)
					More data for this Ligand-Target Pair