BDBM484167 (S)-4-((2,4-dimethyl-3-oxo-1- oxa-4,9- diazaspiro[5.5]undecan-9- yl)methyl)benzonitrile::US10927128, Example 88

SMILES: C[C@@H]1OC2(CCN(Cc3ccc(cc3)C#N)CC2)CN(C)C1=O

InChI Key: InChIKey=NEIHEWURFZIPIV-AWEZNQCLSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484167   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma-1 (Homo sapiens (Human))	BDBM484167 ((S)-4-((2,4-dimethyl-3-oxo-1- oxa-4,9- diazaspiro[...) Show SMILES C[C@@H]1OC2(CCN(Cc3ccc(cc3)C#N)CC2)CN(C)C1=O |r| Show InChI InChI=1S/C18H23N3O2/c1-14-17(22)20(2)13-18(23-14)7-9-21(10-8-18)12-16-5-3-15(11-19)4-6-16/h3-6,14H,7-10,12-13H2,1-2H3/t14-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021)
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