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BDBM484180 8-(2-(3-chloropyridin-2- yl)ethyl)-12-isobutyl-4-oxa- 8,12- diazadispiro[2.1.5.3]tridecane::US10927128, Example 101

SMILES: CC(C)CN1CC2(CC2)OC2(CCN(CCc3ncccc3Cl)CC2)C1

InChI Key: InChIKey=GMHVFOAGNBEGLU-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484180   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sigma-1


(Homo sapiens (Human))		BDBM484180
PNG
(8-(2-(3-chloropyridin-2- yl)ethyl)-12-isobutyl-4-o...)
Show SMILES CC(C)CN1CC2(CC2)OC2(CCN(CCc3ncccc3Cl)CC2)C1
Show InChI InChI=1S/C21H32ClN3O/c1-17(2)14-25-15-20(6-7-20)26-21(16-25)8-12-24(13-9-21)11-5-19-18(22)4-3-10-23-19/h3-4,10,17H,5-9,11-16H2,1-2H3
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
<100n/an/an/an/an/an/an/an/a



ESTEVE PHARMACEUTICALS. S.A.

US Patent


Assay Description
To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...

US Patent US10927128 (2021)

More data for this
Ligand-Target Pair