BDBM484693 US10934297, Compound 86

SMILES: FC(F)Oc1ccc(NC(=O)c2n[nH]c3ccc(cc23)-c2cnn(c2)C2CNC2)cn1

InChI Key: InChIKey=MAPYOBVMOCMQPR-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 484693   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM484693 (US10934297, Compound 86) Show SMILES FC(F)Oc1ccc(NC(=O)c2n[nH]c3ccc(cc23)-c2cnn(c2)C2CNC2)cn1 Show InChI InChI=1S/C20H17F2N7O2/c21-20(22)31-17-4-2-13(7-24-17)26-19(30)18-15-5-11(1-3-16(15)27-28-18)12-6-25-29(10-12)14-8-23-9-14/h1-7,10,14,20,23H,8-9H2,(H,26,30)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	354	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description GSK3β: Each compound is dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-respo...				US Patent US10934297 (2021)
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM484693 (US10934297, Compound 86) Show SMILES FC(F)Oc1ccc(NC(=O)c2n[nH]c3ccc(cc23)-c2cnn(c2)C2CNC2)cn1 Show InChI InChI=1S/C20H17F2N7O2/c21-20(22)31-17-4-2-13(7-24-17)26-19(30)18-15-5-11(1-3-16(15)27-28-18)12-6-25-29(10-12)14-8-23-9-14/h1-7,10,14,20,23H,8-9H2,(H,26,30)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	98	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description DYRK1A: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response...				US Patent US10934297 (2021)
					More data for this Ligand-Target Pair