BDBM484728 US10934297, Compound 141
SMILES: CN1CCC(CC1)n1cc(NC(=O)c2n[nH]c3ccc(cc23)-c2cnn(C)c2)cn1
InChI Key: InChIKey=DQWBYCBUTPEWFQ-UHFFFAOYSA-N
Data: 2 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM484728 (US10934297, Compound 141) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 4 | n/a | n/a | n/a | n/a |
Samumed, LLC US Patent | Assay Description GSK3β: Each compound is dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-respo... | US Patent US10934297 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human)) | BDBM484728 (US10934297, Compound 141) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a |
Samumed, LLC US Patent | Assay Description DYRK1A: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response... | US Patent US10934297 (2021) | |||||||||||
More data for this Ligand-Target Pair |