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SMILES: CN1CCC(CC1)n1cc(cn1)-c1ccc2[nH]nc(C(=O)Nc3ncc(C)s3)c2c1

InChI Key: InChIKey=CDNQBRMCVASTDZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 484731   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM484731 (US10934297, Compound 144) Show SMILES CN1CCC(CC1)n1cc(cn1)-c1ccc2[nH]nc(C(=O)Nc3ncc(C)s3)c2c1 Show InChI InChI=1S/C21H23N7OS/c1-13-10-22-21(30-13)24-20(29)19-17-9-14(3-4-18(17)25-26-19)15-11-23-28(12-15)16-5-7-27(2)8-6-16/h3-4,9-12,16H,5-8H2,1-2H3,(H,25,26)(H,22,24,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.44E+3	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description GSK3β: Each compound is dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-respo...				US Patent US10934297 (2021)
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM484731 (US10934297, Compound 144) Show SMILES CN1CCC(CC1)n1cc(cn1)-c1ccc2[nH]nc(C(=O)Nc3ncc(C)s3)c2c1 Show InChI InChI=1S/C21H23N7OS/c1-13-10-22-21(30-13)24-20(29)19-17-9-14(3-4-18(17)25-26-19)15-11-23-28(12-15)16-5-7-27(2)8-6-16/h3-4,9-12,16H,5-8H2,1-2H3,(H,25,26)(H,22,24,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description DYRK1A: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response...				US Patent US10934297 (2021)
					More data for this Ligand-Target Pair