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SMILES: Cc1[nH]c2c(cnn2c(=O)c1Cc1ccccc1)-c1ccc(Cl)cc1

InChI Key: InChIKey=JALASGSZXXYNAM-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 487174   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
PAS domain-containing serine/threonine-protein kinase [879-1323]


(Homo sapiens (Human))		BDBM487174
PNG
(6-Benzyl-3-(4-chloro-phenyl)-5-methyl-4H-pyrazolo[...)
Show SMILES Cc1[nH]c2c(cnn2c(=O)c1Cc1ccccc1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C20H16ClN3O/c1-13-17(11-14-5-3-2-4-6-14)20(25)24-19(23-13)18(12-22-24)15-7-9-16(21)10-8-15/h2-10,12,23H,11H2,1H3
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PC cid
PC sid
UniChem
US Patent
n/an/a<1.00E+4n/an/an/an/an/an/a



BioEnergenix LLC

US Patent


Assay Description
Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...

US Patent US10953012 (2021)


BindingDB Entry DOI: 10.7270/Q22F7RJN
More data for this
Ligand-Target Pair