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SMILES: COCc1cc(=O)n2nc(Cc3ccccc3)c(-c3ccc(OC)cc3)c2[nH]1

InChI Key: InChIKey=ZIJBJNWPFIPAHZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 487193   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
PAS domain-containing serine/threonine-protein kinase [879-1323]


(Homo sapiens (Human))		BDBM487193
PNG
(2-Benzyl-5-methoxymethyl-3-(4-methoxy-phenyl)-4H-p...)
Show SMILES COCc1cc(=O)n2nc(Cc3ccccc3)c(-c3ccc(OC)cc3)c2[nH]1
Show InChI InChI=1S/C22H21N3O3/c1-27-14-17-13-20(26)25-22(23-17)21(16-8-10-18(28-2)11-9-16)19(24-25)12-15-6-4-3-5-7-15/h3-11,13,23H,12,14H2,1-2H3
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UniChem
US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



BioEnergenix LLC

US Patent


Assay Description
Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...

US Patent US10953012 (2021)


BindingDB Entry DOI: 10.7270/Q22F7RJN
More data for this
Ligand-Target Pair