BDBM48807 4-[(E)-[4-(3-chlorobenzyl)-3-keto-1,4-benzothiazin-2-ylidene]methyl]-N-[2-(4-ethylpiperazino)ethyl]benzamide::4-[(E)-[4-[(3-chlorophenyl)methyl]-3-oxidanylidene-1,4-benzothiazin-2-ylidene]methyl]-N-[2-(4-ethylpiperazin-1-yl)ethyl]benzamide::4-[(E)-[4-[(3-chlorophenyl)methyl]-3-oxo-1,4-benzothiazin-2-ylidene]methyl]-N-[2-(4-ethyl-1-piperazinyl)ethyl]benzamide::4-[(E)-[4-[(3-chlorophenyl)methyl]-3-oxo-1,4-benzothiazin-2-ylidene]methyl]-N-[2-(4-ethylpiperazin-1-yl)ethyl]benzamide::4-{(E)-[4-(3-chlorobenzyl)-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-2-ylidene]methyl}-N-[2-(4-ethylpiperazin-1-yl)ethyl]benzamide::MLS000682555::SMR000311912::cid_16189332

SMILES: CCN1CCN(CCNC(=O)c2ccc(\C=C3\Sc4ccccc4N(Cc4cccc(Cl)c4)C3=O)cc2)CC1

InChI Key: InChIKey=SDTMUAXNMBDCMA-XHLNEMQHSA-N

Data: 2 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 48807   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
eukaryotic translation initiation factor 4 gamma, 1 isoform 4 (Homo sapiens (Human))	BDBM48807 (4-[(E)-[4-(3-chlorobenzyl)-3-keto-1,4-benzothiazin...) Show SMILES CCN1CCN(CCNC(=O)c2ccc(\C=C3\Sc4ccccc4N(Cc4cccc(Cl)c4)C3=O)cc2)CC1 Show InChI InChI=1S/C31H33ClN4O2S/c1-2-34-16-18-35(19-17-34)15-14-33-30(37)25-12-10-23(11-13-25)21-29-31(38)36(22-24-6-5-7-26(32)20-24)27-8-3-4-9-28(27)39-29/h3-13,20-21H,2,14-19,22H2,1H3,(H,33,37)/b29-21+	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation NIH Molecular Libraries Screening Centers Network [MLSC...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2RN3686
					More data for this Ligand-Target Pair
neutrophil cytosolic factor 1 (Homo sapiens (Human))	BDBM48807 (4-[(E)-[4-(3-chlorobenzyl)-3-keto-1,4-benzothiazin...) Show SMILES CCN1CCN(CCNC(=O)c2ccc(\C=C3\Sc4ccccc4N(Cc4cccc(Cl)c4)C3=O)cc2)CC1 Show InChI InChI=1S/C31H33ClN4O2S/c1-2-34-16-18-35(19-17-34)15-14-33-30(37)25-12-10-23(11-13-25)21-29-31(38)36(22-24-6-5-7-26(32)20-24)27-8-3-4-9-28(27)39-29/h3-13,20-21H,2,14-19,22H2,1H3,(H,33,37)/b29-21+	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2M90723
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 2 (Homo sapiens (Human))	BDBM48807 (4-[(E)-[4-(3-chlorobenzyl)-3-keto-1,4-benzothiazin...) Show SMILES CCN1CCN(CCNC(=O)c2ccc(\C=C3\Sc4ccccc4N(Cc4cccc(Cl)c4)C3=O)cc2)CC1 Show InChI InChI=1S/C31H33ClN4O2S/c1-2-34-16-18-35(19-17-34)15-14-33-30(37)25-12-10-23(11-13-25)21-29-31(38)36(22-24-6-5-7-26(32)20-24)27-8-3-4-9-28(27)39-29/h3-13,20-21H,2,14-19,22H2,1H3,(H,33,37)/b29-21+	MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.78E+3	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q21Z42TP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 2 (Homo sapiens (Human))	BDBM48807 (4-[(E)-[4-(3-chlorobenzyl)-3-keto-1,4-benzothiazin...) Show SMILES CCN1CCN(CCNC(=O)c2ccc(\C=C3\Sc4ccccc4N(Cc4cccc(Cl)c4)C3=O)cc2)CC1 Show InChI InChI=1S/C31H33ClN4O2S/c1-2-34-16-18-35(19-17-34)15-14-33-30(37)25-12-10-23(11-13-25)21-29-31(38)36(22-24-6-5-7-26(32)20-24)27-8-3-4-9-28(27)39-29/h3-13,20-21H,2,14-19,22H2,1H3,(H,33,37)/b29-21+	MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	6.53E+3	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q25Q4THK
					More data for this Ligand-Target Pair