BDBM48879 MLS000660477::N-(4-acetylphenyl)-2-(2-nitrothiophen-3-yl)sulfanylacetamide::N-(4-acetylphenyl)-2-[(2-nitro-3-thienyl)thio]acetamide::N-(4-acetylphenyl)-2-[(2-nitro-3-thiophenyl)thio]acetamide::N-(4-acetylphenyl)-2-[(2-nitrothien-3-yl)thio]acetamide::N-(4-ethanoylphenyl)-2-(2-nitrothiophen-3-yl)sulfanyl-ethanamide::SMR000309996::cid_16195563

SMILES: CC(=O)c1ccc(NC(=O)CSc2ccsc2[N+]([O-])=O)cc1

InChI Key: InChIKey=LOQLRFNYEDDFPA-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 48879   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
eukaryotic translation initiation factor 4 gamma, 1 isoform 4 (Homo sapiens (Human))	BDBM48879 (MLS000660477 | N-(4-acetylphenyl)-2-(2-nitrothioph...) Show SMILES CC(=O)c1ccc(NC(=O)CSc2ccsc2[N+]([O-])=O)cc1 Show InChI InChI=1S/C14H12N2O4S2/c1-9(17)10-2-4-11(5-3-10)15-13(18)8-22-12-6-7-21-14(12)16(19)20/h2-7H,8H2,1H3,(H,15,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation NIH Molecular Libraries Screening Centers Network [MLSC...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2RN3686
					More data for this Ligand-Target Pair
BZLF2 (Human herpesvirus 4 type 2)	BDBM48879 (MLS000660477 | N-(4-acetylphenyl)-2-(2-nitrothioph...) Show SMILES CC(=O)c1ccc(NC(=O)CSc2ccsc2[N+]([O-])=O)cc1 Show InChI InChI=1S/C14H12N2O4S2/c1-9(17)10-2-4-11(5-3-10)15-13(18)8-22-12-6-7-21-14(12)16(19)20/h2-7H,8H2,1H3,(H,15,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2057DCW
					More data for this Ligand-Target Pair
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1 (Homo sapiens (Human))	BDBM48879 (MLS000660477 | N-(4-acetylphenyl)-2-(2-nitrothioph...) Show SMILES CC(=O)c1ccc(NC(=O)CSc2ccsc2[N+]([O-])=O)cc1 Show InChI InChI=1S/C14H12N2O4S2/c1-9(17)10-2-4-11(5-3-10)15-13(18)8-22-12-6-7-21-14(12)16(19)20/h2-7H,8H2,1H3,(H,15,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2V986KM
					More data for this Ligand-Target Pair
neuronal munc18-1 binding protein (Rattus norvegicus)	BDBM48879 (MLS000660477 | N-(4-acetylphenyl)-2-(2-nitrothioph...) Show SMILES CC(=O)c1ccc(NC(=O)CSc2ccsc2[N+]([O-])=O)cc1 Show InChI InChI=1S/C14H12N2O4S2/c1-9(17)10-2-4-11(5-3-10)15-13(18)8-22-12-6-7-21-14(12)16(19)20/h2-7H,8H2,1H3,(H,15,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q20P0XFH
					More data for this Ligand-Target Pair
Voltage-gated calcium channel subunit alpha Cav2.2 (Homo sapiens (Human))	BDBM48879 (MLS000660477 | N-(4-acetylphenyl)-2-(2-nitrothioph...) Show SMILES CC(=O)c1ccc(NC(=O)CSc2ccsc2[N+]([O-])=O)cc1 Show InChI InChI=1S/C14H12N2O4S2/c1-9(17)10-2-4-11(5-3-10)15-13(18)8-22-12-6-7-21-14(12)16(19)20/h2-7H,8H2,1H3,(H,15,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute Network...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2PZ578V
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM48879 (MLS000660477 | N-(4-acetylphenyl)-2-(2-nitrothioph...) Show SMILES CC(=O)c1ccc(NC(=O)CSc2ccsc2[N+]([O-])=O)cc1 Show InChI InChI=1S/C14H12N2O4S2/c1-9(17)10-2-4-11(5-3-10)15-13(18)8-22-12-6-7-21-14(12)16(19)20/h2-7H,8H2,1H3,(H,15,18)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q23X8539
					More data for this Ligand-Target Pair