null

SMILES: CN(C)CCN1CCN(CC1=O)c1cccc(Br)c1NC(=O)c1coc(N)n1

InChI Key: InChIKey=HLLNKQZDUDYPAF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 489196   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (Human)	BDBM489196 (US10961233, Example 45) Show SMILES CN(C)CCN1CCN(CC1=O)c1cccc(Br)c1NC(=O)c1coc(N)n1 Show InChI InChI=1S/C18H23BrN6O3/c1-23(2)6-7-24-8-9-25(10-15(24)26)14-5-3-4-12(19)16(14)22-17(27)13-11-28-18(20)21-13/h3-5,11H,6-10H2,1-2H3,(H2,20,21)(H,22,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.5	n/a	n/a	n/a	n/a	n/a	n/a
LIFEARC US Patent					Assay Description 5 μl WT full length PAICS (final assay concentration, fac, 2.5 nM) in basic buffer, added to black, non-binding, 384-well plates (Corning #3575)...				US Patent US10961233 (2021)
					More data for this Ligand-Target Pair