null
SMILES: CN(C)CCCS(=O)(=O)N1CCN(CC1)c1ccc(Br)c(NC(=O)c2coc(N)n2)c1
InChI Key: InChIKey=GTJMWLKWMPRNKA-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (Human) | BDBM489214 (US10961233, Example 69) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
LIFEARC US Patent | Assay Description 5 μl WT full length PAICS (final assay concentration, fac, 2.5 nM) in basic buffer, added to black, non-binding, 384-well plates (Corning #3575)... | US Patent US10961233 (2021) | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |