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SMILES: CC(C)c1c([nH]c2ncnn2c1=O)-c1cnn(c1)C1CCC1

InChI Key: InChIKey=CSEBMDIREZUHDD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492546   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM492546
PNG
(5-(1-cyclobutyl-1H- pyrazol-4-yl)-6-(1- methylethy...)
Show SMILES CC(C)c1c([nH]c2ncnn2c1=O)-c1cnn(c1)C1CCC1
Show InChI InChI=1S/C15H18N6O/c1-9(2)12-13(19-15-16-8-18-21(15)14(12)22)10-6-17-20(7-10)11-4-3-5-11/h6-9,11H,3-5H2,1-2H3,(H,16,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.08n/an/an/an/an/an/a



Merck Sharp & Dohme Corp.

US Patent


Assay Description
In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...

US Patent US10975084 (2021)


BindingDB Entry DOI: 10.7270/Q2K64N61
More data for this
Ligand-Target Pair