BDBM492832 7-((1-phenylethyl)thio)- 3H-[1,2,3]triazolo[4,5- b]pyridin-5-amine::US10981879, Example 2

SMILES: CC(Sc1cc(N)nc2[nH]nnc12)c1ccccc1

InChI Key:

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 492832   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Myeloperoxidase (Homo sapiens (Human))	BDBM492832 (7-((1-phenylethyl)thio)- 3H-[1,2,3]triazolo[4,5- b...) Show SMILES CC(Sc1cc(N)nc2[nH]nnc12)c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen catalog #A12222) which ...				US Patent US10981879 (2021)
					More data for this Ligand-Target Pair
Myeloperoxidase (Homo sapiens (Human))	BDBM492832 (7-((1-phenylethyl)thio)- 3H-[1,2,3]triazolo[4,5- b...) Show SMILES CC(Sc1cc(N)nc2[nH]nnc12)c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description MPO chlorination activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Aminophenyl fluorescein (APF, Invitrogen catal...				US Patent US10981879 (2021)
					More data for this Ligand-Target Pair