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SMILES: Cc1nn(c(Cl)c1CSc1cc(N)nc2[nH]nnc12)-c1ccccc1

InChI Key: InChIKey=KXTAHRPAFDJXNG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 492844   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Myeloperoxidase (Homo sapiens (Human))	BDBM492844 (7-(((5-chloro-3-methyl-1- phenyl-1H-pyrazol-4- yl)...) Show SMILES Cc1nn(c(Cl)c1CSc1cc(N)nc2[nH]nnc12)-c1ccccc1 Show InChI InChI=1S/C16H14ClN7S/c1-9-11(15(17)24(22-9)10-5-3-2-4-6-10)8-25-12-7-13(18)19-16-14(12)20-23-21-16/h2-7H,8H2,1H3,(H3,18,19,20,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen catalog #A12222) which ...				US Patent US10981879 (2021) BindingDB Entry DOI: 10.7270/Q2SN0D3M
					More data for this Ligand-Target Pair
Myeloperoxidase (Homo sapiens (Human))	BDBM492844 (7-(((5-chloro-3-methyl-1- phenyl-1H-pyrazol-4- yl)...) Show SMILES Cc1nn(c(Cl)c1CSc1cc(N)nc2[nH]nnc12)-c1ccccc1 Show InChI InChI=1S/C16H14ClN7S/c1-9-11(15(17)24(22-9)10-5-3-2-4-6-10)8-25-12-7-13(18)19-16-14(12)20-23-21-16/h2-7H,8H2,1H3,(H3,18,19,20,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description MPO chlorination activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Aminophenyl fluorescein (APF, Invitrogen catal...				US Patent US10981879 (2021) BindingDB Entry DOI: 10.7270/Q2SN0D3M
					More data for this Ligand-Target Pair