BDBM493378 US10981917, Example 79

SMILES: O[C@H]1CCCN[C@@H]1CCCn1cnc2cc(Cl)cc(F)c12

InChI Key: InChIKey=PFPAJCIPBXFUHE-OCCSQVGLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 493378   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribose-phosphate pyrophosphokinase 1 (Homo sapiens (Human))	BDBM493378 (US10981917, Example 79) Show SMILES O[C@H]1CCCN[C@@H]1CCCn1cnc2cc(Cl)cc(F)c12 |r| Show InChI InChI=1S/C15H19ClFN3O/c16-10-7-11(17)15-13(8-10)19-9-20(15)6-2-3-12-14(21)4-1-5-18-12/h7-9,12,14,18,21H,1-6H2/t12-,14+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description In order to confirm the biological activities of the compounds prepared in Examples, % inhibition or IC50 values of PRS enzyme (phosphoribosylpyropho...				US Patent US10981917 (2021)
					More data for this Ligand-Target Pair