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SMILES: O\N=C(/NC1CCc2ccc(F)cc12)c1nonc1SCC(=O)NC1CC1

InChI Key: InChIKey=URDSZJUVBGMVBQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 494683   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))		BDBM494683
PNG
(N-cyclopropyl-2-((4-(N-(6-fluoro- 2,3-dihydro-1H-i...)
Show SMILES O\N=C(/NC1CCc2ccc(F)cc12)c1nonc1SCC(=O)NC1CC1
Show InChI InChI=1S/C17H18FN5O3S/c18-10-3-1-9-2-6-13(12(9)7-10)20-16(21-25)15-17(23-26-22-15)27-8-14(24)19-11-4-5-11/h1,3,7,11,13,25H,2,4-6,8H2,(H,19,24)(H,20,21)
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US Patent
n/an/a 51.2n/an/an/an/an/an/a



Merck Sharp & Dohme Corp.

US Patent


Assay Description
HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...

US Patent US10988487 (2021)

More data for this
Ligand-Target Pair