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SMILES: CC(O)CNC(=O)CNc1nonc1\C(N[C@H]1CCc2ccc(F)cc12)=N\O

InChI Key: InChIKey=WVNXGNLPHOMCSB-NCWAPJAISA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 494783   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))		BDBM494783
PNG
(N~2~-(4-{N-[(1S)-6-fluoro- 2,3-dihydro-1H-inden-1-...)
Show SMILES CC(O)CNC(=O)CNc1nonc1\C(N[C@H]1CCc2ccc(F)cc12)=N\O |r|
Show InChI InChI=1S/C17H21FN6O4/c1-9(25)7-19-14(26)8-20-16-15(23-28-24-16)17(22-27)21-13-5-3-10-2-4-11(18)6-12(10)13/h2,4,6,9,13,25,27H,3,5,7-8H2,1H3,(H,19,26)(H,20,24)(H,21,22)/t9?,13-/m0/s1
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MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 54.1n/an/an/an/an/an/a



Merck Sharp & Dohme Corp.

US Patent


Assay Description
HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...

US Patent US10988487 (2021)

More data for this
Ligand-Target Pair