BDBM494804 N-{2-[(4-{N-[(7S)-4- fluorobicyclo[4.2.0]octa-1,3,5- trien-7-yl]-N'- hydroxycarbamimidoyl}-1,2,5- oxadiazol-3-yl)sulfanyl]ethyl}- 2-hydroxyacetamide::US10988487, Example 200

SMILES: OCC(=O)NCCSc1nonc1\C(N[C@H]1Cc2ccc(F)cc12)=N\O

InChI Key: InChIKey=WSUUKTIVQDRZHX-NSHDSACASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 494804   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM494804 (N-{2-[(4-{N-[(7S)-4- fluorobicyclo[4.2.0]octa-1,3,...) Show SMILES OCC(=O)NCCSc1nonc1\C(N[C@H]1Cc2ccc(F)cc12)=N\O |r| Show InChI InChI=1S/C15H16FN5O4S/c16-9-2-1-8-5-11(10(8)6-9)18-14(19-24)13-15(21-25-20-13)26-4-3-17-12(23)7-22/h1-2,6,11,22,24H,3-5,7H2,(H,17,23)(H,18,19)/t11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	59.3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...				US Patent US10988487 (2021)
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